Gene

slf2

ID
ZDB-GENE-081107-61
Name
SMC5/6 complex localization factor 2
Symbol
slf2 Nomenclature History
Previous Names
  • fam178a
  • si:dkey-19p15.8
  • si:dkey-19p15.9
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to act upstream of or within DNA repair. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in mosaic variegated aneuploidy syndrome. Orthologous to human SLF2 (SMC5-SMC6 complex localization factor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa13972Allele with one point mutationUnknownSplice SiteENU
sa15823Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With slf2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Atelis syndrome 1 620184
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Associated With slf2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR044276 Coiled-coil SMC6 And NSE5 INteracting (CANIN) domain
Family IPR026161 FAM178 family
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Domain Details Per Protein
Protein Additional Resources Length Coiled-coil SMC6 And NSE5 INteracting (CANIN) domain FAM178 family
UniProtKB:A0A8M1RDX3 InterPro 1216
UniProtKB:A0A8M2B2M7 InterPro 1212
UniProtKB:A0A8M9PBD2 InterPro 850
UniProtKB:A0A8M9Q4X8 InterPro 937
UniProtKB:A0A8M9PMW4 InterPro 280
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 13
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA slf2-201 (1) Ensembl 5,531 nt
mRNA slf2-202 (1) Ensembl 585 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-116E5ZFIN Curated Data
Contained inBACDKEY-19P15ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanSLF210
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseSlf219
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations