ZFIN is now using GRCz12tu for Genomic Data
Gene
fap
- ID
- ZDB-GENE-081104-439
- Name
- fibroblast activation protein, alpha
- Symbol
- fap Nomenclature History
- Previous Names
-
- si:dkey-81j5.3
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable dipeptidyl-peptidase activity. Predicted to be involved in proteolysis. Predicted to be active in plasma membrane. Is expressed in neurocranium. Orthologous to human FAP (fibroblast activation protein alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Wei et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Wei et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR002471 | Peptidase S9, serine active site |
| Domain | IPR001375 | Peptidase S9, prolyl oligopeptidase, catalytic domain |
| Domain | IPR002469 | Dipeptidylpeptidase IV, N-terminal domain |
| Domain | IPR040522 | Dipeptidyl peptidase 4, low complexity region |
| Family | IPR050278 | Serine protease S9B/DPPIV |
| Homologous_superfamily | IPR029058 | Alpha/Beta hydrolase fold |
Domain Details Per Protein
| Protein | Additional Resources | Length | Alpha/Beta hydrolase fold | Dipeptidyl peptidase 4, low complexity region | Dipeptidylpeptidase IV, N-terminal domain | Peptidase S9, prolyl oligopeptidase, catalytic domain | Peptidase S9, serine active site | Serine protease S9B/DPPIV |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:B0R1C4 | InterPro | 750 | ||||||
| UniProtKB:A0ACD6B6N9 | InterPro | 750 | ||||||
| UniProtKB:A0AC58GI46 | InterPro | 447 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers