Gene

pttg1

ID

ZDB-GENE-081104-345

Name

PTTG1 regulator of sister chromatid separation, securin

Symbol

pttg1 Nomenclature History

Previous Names

si:ch211-232m8.6
si:dkey-192o1.2 (1)
si:dkey-23o10.2

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to be involved in homologous chromosome segregation and negative regulation of mitotic sister chromatid separation. Predicted to localize to nucleus. Orthologous to several human genes including PTTG1 (PTTG1 regulator of sister chromatid separation, securin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Liu et al., 2011

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pttg1 Human Ortholog

No data available

Associated With pttg1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR006940	Securin sister-chromatid separation inhibitor

Domain Details Per Protein

Protein	Length	Securin sister-chromatid separation inhibitor
UniProtKB:B8A4J0 InterPro	182

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pttg1-201 (1) Ensembl	Havana	824 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	pttg1-002 (1) Ensembl	Havana	855 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	pttg1-003 (1) Ensembl	Havana	771 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations