Gene

nr0b2b

ID
ZDB-GENE-080403-9
Name
nuclear receptor subfamily 0, group B, member 2b
Symbol
nr0b2b Nomenclature History
Previous Names
  • NR0B2-B (1)
  • gb:dq017630
  • SHP-B (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable transcription corepressor activity. Predicted to be involved in circadian rhythm; negative regulation of DNA-binding transcription factor activity; and negative regulation of transcription by RNA polymerase II. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human NR0B2 (nuclear receptor subfamily 0 group B member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from Thisse et al., 2008
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nr0b2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
obesity Alliance Obesity, mild, early-onset 601665
Associated With nr0b2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Family IPR033544 Nuclear receptor subfamily 0 group B member 1/2
Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
Domain Details Per Protein
Protein Length Nuclear hormone receptor, ligand-binding domain Nuclear hormone receptor-like domain superfamily Nuclear receptor subfamily 0 group B member 1/2
UniProtKB:A0A0R4IFS6 241
UniProtKB:Q1L676 235
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations