Gene
nr0b2b
- ID
- ZDB-GENE-080403-9
- Name
- nuclear receptor subfamily 0, group B, member 2b
- Symbol
- nr0b2b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human NR0B2 (nuclear receptor subfamily 0 group B member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- dq017630 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Nuclear receptor subfamily 0 group B member 1/2 |
|---|---|---|---|---|---|
| UniProtKB:A0AB13A8L2 | InterPro | 247 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nr0b2b-201
(1)
|
Ensembl | 726 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | Fosmid | ZFOS-1496B1 | ZFIN Curated Data | |
| Encodes | EST | dq017630 | Bertrand et al., 2007 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001386343 (1) | 1064 nt | ||
| Genomic | GenBank:CU905504 (2) | 41681 nt | ||
| Polypeptide | UniProtKB:A0AB13A8L2 (1) | 247 aa |
- Gao, S.Y., Zhao, J.C., Xia, Q., Sun, C., Aili, M., Talifu, A., Huo, S.X., Zhang, Y., Li, Z.J. (2024) Evaluation of the hepatotoxicity of Psoralea corylifolia L. based on a zebrafish model. Frontiers in pharmacology. 15:13086551308655
- Xiong, F., Cao, L., Wu, X.M., Chang, M.X. (2020) The function of zebrafish gpbar1 in antiviral response and lipid metabolism. Developmental and comparative immunology. 116:103955
- Cheng, Y.Y., Tao, W.J., Chen, J.L., Sun, L.N., Zhou, L.Y., Song, Q., Wang, D.S. (2015) Genome-wide identification, evolution and expression analysis of nuclear receptor superfamily in Nile tilapia, Oreochromis niloticus. Gene. 569(1):141-52
- Long, Y., Li, L., Li, Q., He, X., and Cui, Z. (2012) Transcriptomic characterization of temperature stress responses in larval zebrafish. PLoS One. 7(5):e37209
- Bertrand, S., Thisse, B., Tavares, R., Sachs, L., Chaumot, A., Bardet, P.L., Escrivà, H., Duffraisse, M., Marchand, O., Safi, R., Thisse, C., and Laudet, V. (2007) Unexpected Novel Relational Links Uncovered by Extensive Developmental Profiling of Nuclear Receptor Expression. PLoS Genetics. 3(11):e188
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