ZFIN is now using GRCz12tu for Genomic Data
Gene
pard3ba
- ID
- ZDB-GENE-080225-12
- Name
- par-3 family cell polarity regulator beta a
- Symbol
- pard3ba Nomenclature History
- Previous Names
-
- im:7153558
- im:7153839
- si:ch1073-345a8.1
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in several processes, including establishment of cell polarity; establishment of centrosome localization; and establishment or maintenance of epithelial cell apical/basal polarity. Predicted to be located in bicellular tight junction and membrane. Predicted to be active in several cellular components, including adherens junction; apical junction complex; and apical plasma membrane. Is expressed in several structures, including EVL; intermediate cell mass of mesoderm; periderm; sensory system; and tegmentum. Orthologous to human PARD3B (par-3 family cell polarity regulator beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7153839 (1 image)
- IMAGE:7153558 (20 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Par3/HAL, N-terminal | Partitioning defective 3 homolog | PDZ domain | PDZ superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6YYR6 | InterPro | 1199 | ||||
| UniProtKB:A0A0H2UKQ5 | InterPro | 1024 | ||||
| UniProtKB:A0A8M6Z6K7 | InterPro | 1037 | ||||
| UniProtKB:A0A8M9Q2H5 | InterPro | 839 | ||||
| UniProtKB:A0A8M6Z6J6 | InterPro | 1185 |
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- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch1073-345a8.1-201
(1)
|
Ensembl | 542 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-103I6 | ZFIN Curated Data | |
| Contained in | Fosmid | CH1073-345A8 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:7153558 | Thisse et al., 2004 | |
| Encodes | EST | IMAGE:7153839 | Thisse et al., 2004 |
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- Genome Browsers
| Type | Accession # | Genome Assembly | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001328558 (1) | 3599 nt | ||
| Genomic | GenBank:BX004814 (1) | 171710 nt | ||
| Polypeptide | UniProtKB:A0A8M6YYR6 (1) | 1199 aa |
- Tang, W., Davidson, J.D., Zhang, G., Conen, K.E., Fang, J., Serluca, F., Li, J., Xiong, X., Coble, M., Tsai, T., Molind, G., Fawcett, C.H., Sanchez, E., Zhu, P., Couzin, I.D., Fishman, M.C. (2020) Genetic Control of Collective Behavior in Zebrafish. iScience. 23:100942
- Sun, Y., Zhang, B., Luo, L., Shi, D.L., Wang, H., Cui, Z., Huang, H., Cao, Y., Shu, X., Zhang, W., Zhou, J., Li, Y., Du, J., Zhao, Q., Chen, J., Zhong, H., Zhong, T.P., Li, L., Xiong, J.W., Peng, J., Xiao, W., Zhang, J., Yao, J., Yin, Z., Mo, X., Peng, G., Zhu, J., Chen, Y., Zhou, Y., Liu, D., Pan, W., Zhang, Y., Ruan, H., Liu, F., Zhu, Z., Meng, A., ZAKOC Consortium (2019) Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9. Genome research. 30(1):118-26
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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