rac3b

ID

ZDB-GENE-080220-21

Name

Rac family small GTPase 3b

Symbol

rac3b Nomenclature History

Previous Names

zgc:175209 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Acts upstream of or within actomyosin structure organization and rhombomere boundary formation. Predicted to be active in several cellular components, including cytoplasmic vesicle; cytoskeleton; and neuron projection. Is expressed in rhombomere and skeletal muscle. Orthologous to human RAC3 (Rac family small GTPase 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rac3b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with structural brain anomalies and dysmorphic facies	618577

Associated With rac3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR005225	Small GTP-binding domain
Family	IPR001806	Small GTPase
Family	IPR003578	Small GTPase Rho
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase