Gene

slc2a10

ID

ZDB-GENE-080204-6

Name

solute carrier family 2 member 10

Symbol

slc2a10 Nomenclature History

Previous Names

Glut10 (1)
zgc:171488 (1)
zglut10 (1)

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have transmembrane transporter activity. Involved in circulatory system development and notochord development. Predicted to localize to endomembrane system; integral component of membrane; and perinuclear region of cytoplasm. Is expressed in several structures, including fin; hatching gland; nervous system; pectoral fin bud; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in arterial tortuosity syndrome. Orthologous to human SLC2A10 (solute carrier family 2 member 10).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Willaert et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc2a10 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
arterial tortuosity syndrome	Alliance	Arterial tortuosity syndrome	208050

Associated With slc2a10 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR005829	Sugar transporter, conserved site
Domain	IPR020846	Major facilitator superfamily domain
Family	IPR003663	Sugar/inositol transporter
Family	IPR005828	Major facilitator, sugar transporter-like
Family	IPR050820	Major Facilitator Superfamily Sugar Transporter
Homologous_superfamily	IPR036259	MFS transporter superfamily