Gene

pign

ID
ZDB-GENE-080204-114
Name
phosphatidylinositol glycan anchor biosynthesis, class N
Symbol
pign Nomenclature History
Previous Names
  • zgc:172324
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have mannose-ethanolamine phosphotransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to localize to endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in multiple congenital anomalies-hypotonia-seizures syndrome 1. Orthologous to human PIGN (phosphatidylinositol glycan anchor biosynthesis class N).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pign Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
multiple congenital anomalies-hypotonia-seizures syndrome 1 Alliance Multiple congenital anomalies-hypotonia-seizures syndrome 1 614080
Associated With pign Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017852 GPI ethanolamine phosphate transferase 1, C-terminal
Domain IPR037671 GPI ethanolamine phosphate transferase 1, N-terminal
Family IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
Family IPR007070 GPI ethanolamine phosphate transferase 1
Homologous_superfamily IPR017850 Alkaline-phosphatase-like, core domain superfamily
Domain Details Per Protein
Protein Length Alkaline-phosphatase-like, core domain superfamily GPI ethanolamine phosphate transferase 1 GPI ethanolamine phosphate transferase 1, C-terminal GPI ethanolamine phosphate transferase 1, N-terminal Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
UniProtKB:A0A8M3B6M9 571
UniProtKB:E7EXW2 932
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations