Gene
csf2rb
- ID
- ZDB-GENE-080115-1
- Name
- colony stimulating factor 2 receptor subunit beta
- Symbol
- csf2rb Nomenclature History
- Previous Names
-
- il-3rbc (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Orthologous to human CSF2RB (colony stimulating factor 2 receptor subunit beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
pulmonary alveolar proteinosis | Alliance | Surfactant metabolism dysfunction, pulmonary, 5 | 614370 |
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Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold |
---|---|---|---|---|---|
UniProtKB:A0A8M9P3Q9 | InterPro | 684 | |||
UniProtKB:A8WHB0 | InterPro | 696 | |||
UniProtKB:F1Q6U2 | InterPro | 685 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
csf2rb-201
(1)
|
Ensembl | 6,084 nt | ||
mRNA |
csf2rb-202
(1)
|
Ensembl | 2,322 nt |
1 - 2 of 2
Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-261F22 | ||
Contained in | BAC | DKEY-110G7 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001113733 (1) | 2322 nt | ||
Genomic | GenBank:CR812472 (1) | 194804 nt | ||
Polypeptide | UniProtKB:A8WHB0 (1) | 696 aa |
- Lin, X., Zhou, Q., Zhao, C., Lin, G., Xu, J., Wen, Z. (2019) An Ectoderm-Derived Myeloid-like Cell Population Functions as Antigen Transporters for Langerhans Cells in Zebrafish Epidermis. Developmental Cell. 49(4):605-617.e5
- Anelli, V., Santoriello, C., Distel, M., Köster, R.W., Ciccarelli, F.D., and Mione, M. (2009) Global repression of cancer gene expression in a zebrafish model of melanoma is linked to epigenetic regulation. Zebrafish. 6(4):417-424
- Liongue, C., and Ward, A.C. (2007) Evolution of Class I cytokine receptors. BMC Evolutionary Biology. 7(1):120
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