Gene
dnajc6
- ID
- ZDB-GENE-080104-2
- Name
- DnaJ (Hsp40) homolog, subfamily C, member 6
- Symbol
- dnajc6 Nomenclature History
- Previous Names
-
- Aux (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable clathrin binding activity. Predicted to be involved in clathrin-dependent endocytosis and synaptic vesicle uncoating. Located in cytosol and perinuclear region of cytoplasm. Is expressed in hindbrain; inner ear; neural rod; otic vesicle; and spinal cord. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 19A. Orthologous to human DNAJC6 (DnaJ heat shock protein family (Hsp40) member C6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Bai et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Parkinson's disease 19A | Alliance | Parkinson disease 19a, juvenile-onset | 615528 |
| Parkinson's disease 19A | Alliance | Parkinson disease 19b, early-onset | 615528 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001623 | DnaJ domain |
| Domain | IPR014020 | Tensin phosphatase, C2 domain |
| Domain | IPR029023 | Tensin-type phosphatase domain |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR036869 | Chaperone J-domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C2 domain superfamily | Chaperone J-domain superfamily | DnaJ domain | Protein-tyrosine phosphatase-like | Tensin phosphatase, C2 domain | Tensin-type phosphatase domain |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9Q0M0 | InterPro | 917 | ||||||
| UniProtKB:A0A8M9PF24 | InterPro | 742 | ||||||
| UniProtKB:A0A8M9Q4I9 | InterPro | 748 | ||||||
| UniProtKB:A0A8M9QG43 | InterPro | 974 | ||||||
| UniProtKB:A0A8M9Q219 | InterPro | 764 | ||||||
| UniProtKB:A0A8M9QB30 | InterPro | 954 | ||||||
| UniProtKB:A0A8M9Q6X2 | InterPro | 979 | ||||||
| UniProtKB:A0A8M3B0J3 | InterPro | 970 | ||||||
| UniProtKB:A0A8M9PRW9 | InterPro | 773 | ||||||
| UniProtKB:A0A8M9PRF3 | InterPro | 773 | ||||||
| UniProtKB:A0A8M9PMW6 | InterPro | 948 | ||||||
| UniProtKB:A0A8M9PY08 | InterPro | 764 | ||||||
| UniProtKB:A0A8M9P987 | InterPro | 742 | ||||||
| UniProtKB:A0A8M9PYN9 | InterPro | 748 | ||||||
| UniProtKB:A0AB32TT63 | InterPro | 908 | ||||||
| UniProtKB:A0AB32TXJ4 | InterPro | 960 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dnajc6-201
(1)
|
Ensembl | 7,250 nt | ||
| mRNA |
dnajc6-203
(1)
|
Ensembl | 2,673 nt | ||
| mRNA |
dnajc6-204
(1)
|
Ensembl | 2,616 nt | ||
| mRNA |
dnajc6-205
(1)
|
Ensembl | 2,700 nt | ||
| mRNA |
dnajc6-206
(1)
|
Ensembl | 2,604 nt | ||
| mRNA |
dnajc6-207
(1)
|
Ensembl | 2,649 nt | ||
| mRNA |
dnajc6-208
(1)
|
Ensembl | 2,613 nt | ||
| mRNA |
dnajc6-209
(1)
|
Ensembl | 2,742 nt | ||
| ncRNA |
dnajc6-002
(1)
|
Ensembl | 560 nt |
Interactions and Pathways
No data available
Plasmids
No data available