ZFIN is now using GRCz12tu for Genomic Data
Gene
recql5
- ID
- ZDB-GENE-071214-1
- Name
- RecQ helicase-like 5
- Symbol
- recql5 Nomenclature History
- Previous Names
-
- recql5l
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable several functions, including 3'-5' DNA helicase activity; ATP binding activity; and nucleic acid binding activity. Acts upstream of or within negative regulation of mitotic recombination. Predicted to be located in chromosome and nucleoplasm. Is expressed in several structures, including otic vesicle; pericardial region; presumptive neural retina; retina; and ventricular system. Orthologous to human RECQL5 (RecQ like helicase 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Xie et al., 2007
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001650 | Helicase, C-terminal domain-like |
| Domain | IPR010716 | RecQ helicase-like 5 |
| Domain | IPR011545 | DEAD/DEAH-box helicase domain |
| Domain | IPR013257 | Set2 Rpb1 interacting domain |
| Domain | IPR014001 | Helicase superfamily 1/2, ATP-binding domain |
| Domain | IPR032284 | ATP-dependent DNA helicase RecQ, zinc-binding domain |
| Family | IPR004589 | DNA helicase, ATP-dependent, RecQ type |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | ATP-dependent DNA helicase RecQ, zinc-binding domain | DEAD/DEAH-box helicase domain | DNA helicase, ATP-dependent, RecQ type | Helicase, C-terminal domain-like | Helicase superfamily 1/2, ATP-binding domain | P-loop containing nucleoside triphosphate hydrolase | RecQ helicase-like 5 | Set2 Rpb1 interacting domain |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:X1WCM8 | InterPro | 933 | ||||||||
| UniProtKB:A0AC58J4C7 | InterPro | 894 | ||||||||
| UniProtKB:A0AC58J4C8 | InterPro | 894 | ||||||||
| UniProtKB:A0AC58J4D4 | InterPro | 894 | ||||||||
| UniProtKB:A0AC58J4E8 | InterPro | 933 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
recql5-201
(1)
|
Ensembl | 3,085 nt | ||
| mRNA |
recql5-202
(1)
|
Ensembl | 2,628 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers