itgb8

ID

ZDB-GENE-071213-3

Name

integrin subunit beta 8

Symbol

itgb8 Nomenclature History

Previous Names

im:6912383
si:ch1073-83d9.2

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Acts upstream of or within angiogenesis and endothelial cell proliferation. Predicted to be located in plasma membrane. Is expressed in head. Orthologous to human ITGB8 (integrin subunit beta 8).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6912383 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With itgb8 Human Ortholog

No data available

Associated With itgb8 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002369	Integrin beta subunit, VWA domain
Domain	IPR012896	Integrin beta subunit, tail
Domain	IPR013111	Epidermal growth factor-like domain, extracellular
Domain	IPR016201	PSI domain
Domain	IPR033760	Integrin beta N-terminal
Domain	IPR057073	Integrin beta, epidermal growth factor-like domain 2
Family	IPR015812	Integrin beta subunit
Homologous_superfamily	IPR032695	Integrin domain superfamily
Homologous_superfamily	IPR036349	Integrin beta tail domain superfamily
Homologous_superfamily	IPR036465	von Willebrand factor A-like domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PB88	InterPro	719
UniProtKB:A0AC58HZP3	InterPro	399
UniProtKB:A0AC58HZQ0	InterPro	779
UniProtKB:A0AC58HZR0	InterPro	632
UniProtKB:A0AC58HZS1	InterPro	399