Gene

adam10b

ID
ZDB-GENE-071115-1
Name
ADAM metallopeptidase domain 10b
Symbol
adam10b Nomenclature History
Previous Names
  • zgc:64203
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have metalloendopeptidase activity involved in amyloid precursor protein catabolic process. Predicted to be involved in Notch signaling pathway and PMA-inducible membrane protein ectodomain proteolysis. Predicted to localize to synaptic membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease 18 and reticulate acropigmentation of Kitamura. Orthologous to human ADAM10 (ADAM metallopeptidase domain 10).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adam10b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Alzheimer's disease 18 Alliance {Alzheimer disease 18, susceptibility to} 615590
reticulate acropigmentation of Kitamura Alliance Reticulate acropigmentation of Kitamura 615537
Associated With adam10b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein Length
UniProtKB:A0A8M9PGZ4 669
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations