Gene

ganaba

ID

ZDB-GENE-070928-36

Name

glucosidase II alpha subunit a

Symbol

ganaba Nomenclature History

Previous Names

zgc:171967

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have carbohydrate binding activity and hydrolase activity, hydrolyzing O-glycosyl compounds. Predicted to be involved in carbohydrate metabolic process. Human ortholog(s) of this gene implicated in polycystic kidney disease; polycystic kidney disease 3; and polycystic liver disease. Orthologous to human GANAB (glucosidase II alpha subunit).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ganaba Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
polycystic kidney disease 3	Alliance	Polycystic kidney disease 3	600666

Associated With ganaba Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR030458	Glycosyl hydrolases family 31, active site
Domain	IPR000322	Glycoside hydrolase family 31, TIM barrel domain
Domain	IPR025887	Glycoside hydrolase family 31, N-terminal domain
Domain	IPR048395	Glycosyl hydrolase family 31, C-terminal domain
Homologous_superfamily	IPR011013	Galactose mutarotase-like domain superfamily
Homologous_superfamily	IPR013780	Glycosyl hydrolase, all-beta
Homologous_superfamily	IPR017853	Glycoside hydrolase superfamily

Domain Details Per Protein

Protein	Length	Galactose mutarotase-like domain superfamily	Glycoside hydrolase family 31, N-terminal domain	Glycoside hydrolase family 31, TIM barrel domain	Glycoside hydrolase superfamily	Glycosyl hydrolase, all-beta	Glycosyl hydrolase family 31, C-terminal domain	Glycosyl hydrolases family 31, active site
UniProtKB:A0A8M3BA22 InterPro	984
UniProtKB:A0A8M9QDG6 InterPro	939
UniProtKB:B3DIZ3 InterPro	917

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	zgc:171967-201 (1) Ensembl	Havana	567 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	zgc:171967-202 (1) Ensembl	Havana	548 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations