Gene
bpifcl
- ID
- ZDB-GENE-070912-360
- Name
- BPI fold containing family C, like
- Symbol
- bpifcl Nomenclature History
- Previous Names
-
- LBP (1)
- si:dkey-11f4.4
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable lipid binding activity. Predicted to be involved in defense response to Gram-negative bacterium and innate immune response. Predicted to act upstream of or within defense response to bacterium and immune system process. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in brain.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Moriya et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001124 | Lipid-binding serum glycoprotein, C-terminal |
Domain | IPR017942 | Lipid-binding serum glycoprotein, N-terminal |
Family | IPR030675 | Lipid binding protein BPI/LBP |
Family | IPR032942 | BPI/LBP/Plunc family |
Homologous_superfamily | IPR017943 | Bactericidal permeability-increasing protein, alpha/beta domain superfamily |
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Domain Details Per Protein
Protein | Additional Resources | Length | Bactericidal permeability-increasing protein, alpha/beta domain superfamily | BPI/LBP/Plunc family | Lipid binding protein BPI/LBP | Lipid-binding serum glycoprotein, C-terminal | Lipid-binding serum glycoprotein, N-terminal |
---|---|---|---|---|---|---|---|
UniProtKB:A0A0R4IR32 | InterPro | 472 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
bpifcl-201
(1)
|
Ensembl | 1,918 nt | ||
mRNA |
bpifcl-202
(1)
|
Ensembl | 638 nt | ||
mRNA |
bpifcl-203
(1)
|
Ensembl | 296 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-11F4 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:XM_001342726 (1) | 1933 nt | ||
Genomic | GenBank:CR753874 (1) | 177524 nt | ||
Polypeptide | UniProtKB:A0A0R4IR32 (1) | 472 aa |
No data available
- Yeh, T.H., Liu, H.F., Li, Y.W., Lu, C.S., Shih, H.Y., Chiu, C.C., Lin, S.J., Huang, Y.C., Cheng, Y.C. (2018) C9orf72 is essential for neurodevelopment and motility mediated by cyclin G1. Experimental neurology. 304:114-124
- Moriya, S., Tahsin, N., Parhar, I.S. (2017) Bpifcl modulates kiss2 expression under the influence of 11-ketotestosterone in female zebrafish. Scientific Reports. 7:7926
- Pietretti, D., Spaink, H.P., Falco, A., Forlenza, M., and Wiegertjes, G.F. (2013) Accessory molecules for Toll-like receptors in Teleost fish. Identification of TLR4 interactor with leucine-rich repeats (TRIL). Molecular immunology. 56(4):745-756
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