Gene
ephb1
- ID
- ZDB-GENE-070912-219
- Name
- EPH receptor B1
- Symbol
- ephb1 Nomenclature History
- Previous Names
-
- si:ch211-234b19.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity and ephrin receptor activity. Predicted to be involved in epithelium development and system development. Predicted to act upstream of or within several processes, including cell adhesion; cell surface receptor protein tyrosine kinase signaling pathway; and protein phosphorylation. Predicted to be located in dendrite; early endosome membrane; and plasma membrane.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zheng et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR008266 | Tyrosine-protein kinase, active site |
Binding_site | IPR017441 | Protein kinase, ATP binding site |
Conserved_site | IPR001426 | Tyrosine-protein kinase, receptor class V, conserved site |
Domain | IPR000719 | Protein kinase domain |
Domain | IPR001090 | Ephrin receptor ligand binding domain |
Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
Domain | IPR001660 | Sterile alpha motif domain |
Domain | IPR003961 | Fibronectin type III |
Domain | IPR020635 | Tyrosine-protein kinase, catalytic domain |
Domain | IPR027936 | Ephrin receptor, transmembrane domain |
Domain | IPR042819 | EphB1 , SAM domain |
Family | IPR016257 | Ephrin receptor type-A /type-B |
Family | IPR050449 | Ephrin receptor tyrosine kinases |
Homologous_superfamily | IPR008979 | Galactose-binding-like domain superfamily |
Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Homologous_superfamily | IPR013761 | Sterile alpha motif/pointed domain superfamily |
Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
Domain Details Per Protein
Protein | Additional Resources | Length | EphB1 , SAM domain | Ephrin receptor ligand binding domain | Ephrin receptor, transmembrane domain | Ephrin receptor type-A /type-B | Ephrin receptor tyrosine kinases | Fibronectin type III | Fibronectin type III superfamily | Galactose-binding-like domain superfamily | Growth factor receptor cysteine-rich domain superfamily | Immunoglobulin-like fold | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine-threonine/tyrosine-protein kinase, catalytic domain | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily | Tyrosine-protein kinase, active site | Tyrosine-protein kinase, catalytic domain | Tyrosine-protein kinase, receptor class V, conserved site |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M6Z303 | InterPro | 1011 |
Interactions and Pathways
No data available
Plasmids
No data available