ZFIN is now using GRCz12tu for Genomic Data
Gene
si:ch211-195h23.3
- ID
- ZDB-GENE-070912-174
- Name
- si:ch211-195h23.3
- Symbol
- si:ch211-195h23.3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable GTP binding activity and GTPase activity. Acts upstream of or within negative regulation of NF-kappaB transcription factor activity. Located in nucleus. Is expressed in kidney and spleen. Human ortholog(s) of this gene implicated in inflammatory bowel disease 30. Orthologous to human CARD8 (caspase recruitment domain family member 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chang et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | CARD8/ASC/NALP1, CARD domain | CARD domain | Death-like domain superfamily | FIIND domain | NLRP Inflammasome |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QAJ2 | InterPro | 658 | |||||
| UniProtKB:A0A8M9QJG0 | InterPro | 469 | |||||
| UniProtKB:A0A8M9QF56 | InterPro | 917 | |||||
| UniProtKB:A0A8M9QAI5 | InterPro | 998 | |||||
| UniProtKB:A0A8M9PRT1 | InterPro | 730 | |||||
| UniProtKB:A0A8M9PRS7 | InterPro | 996 | |||||
| UniProtKB:B0V1H3 | InterPro | 478 | |||||
| UniProtKB:A0A8M9Q4E9 | InterPro | 1001 | |||||
| UniProtKB:A0A8M9QAI8 | InterPro | 970 | |||||
| UniProtKB:A0AB32TTJ9 | InterPro | 458 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-195h23.3-201
(1)
|
Ensembl | 1,830 nt |
Interactions and Pathways
No data available
Plasmids
No data available