Gene
map3k3
- ID
- ZDB-GENE-070910-1
- Name
- mitogen-activated protein kinase kinase kinase 3
- Symbol
- map3k3 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within anterior/posterior axis specification and heart development. Predicted to be active in cytoplasm. Orthologous to human MAP3K3 (mitogen-activated protein kinase kinase kinase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Lu et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Hong et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Cerebral cavernous malformations 5 | 621032 |
1 - 1 of 1
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Mitogen-activated protein kinase kinase kinase 2/3, PB1 domain | PB1 domain | PB1-like domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:X1WGZ3 | InterPro | 620 |
1 - 1 of 1
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
map3k3-201
(1)
|
Ensembl | 1,881 nt | ||
| mRNA |
map3k3-202
(1)
|
Ensembl | 5,003 nt | ||
| mRNA |
map3k3-203
(1)
|
Ensembl | 1,827 nt |
1 - 3 of 3
Interactions and Pathways
No data available
Plasmids
No data available