Gene

pcsk5b

ID
ZDB-GENE-070822-7
Name
proprotein convertase subtilisin/kexin type 5b
Symbol
pcsk5b Nomenclature History
Previous Names
  • pc5.2 (1)
  • pcsk5.2 (1)
  • zgc:165659
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have serine-type endopeptidase activity. Predicted to be involved in peptide hormone processing. Predicted to localize to integral component of Golgi membrane and trans-Golgi network. Is expressed in several structures, including digestive system; fin bud; nervous system; pleuroperitoneal region; and tail bud. Orthologous to human PCSK5 (proprotein convertase subtilisin/kexin type 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pcsk5b Human Ortholog
No data available
Associated With pcsk5b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR022398 Peptidase S8, subtilisin, His-active site
Active_site IPR023827 Peptidase S8, subtilisin, Asp-active site
Active_site IPR023828 Peptidase S8, subtilisin, Ser-active site
Domain IPR000209 Peptidase S8/S53 domain
Domain IPR002884 P domain
Domain IPR010909 PLAC
Domain IPR032778 Growth factor receptor domain 4
Domain IPR032815 Peptidase S8, pro-domain
Domain IPR034182 Kexin/furin catalytic domain
Family IPR015500 Peptidase S8, subtilisin-related
Homologous_superfamily IPR008979 Galactose-binding-like domain superfamily
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR036852 Peptidase S8/S53 domain superfamily
Homologous_superfamily IPR038466 Peptidase S8, pro-domain superfamily
Repeat IPR006212 Furin-like repeat
Domain Details Per Protein
Protein Length Furin-like repeat Galactose-binding-like domain superfamily Growth factor receptor cysteine-rich domain superfamily Growth factor receptor domain 4 Kexin/furin catalytic domain P domain Peptidase S8, pro-domain Peptidase S8, pro-domain superfamily Peptidase S8/S53 domain Peptidase S8/S53 domain superfamily Peptidase S8, subtilisin, Asp-active site Peptidase S8, subtilisin, His-active site Peptidase S8, subtilisin-related Peptidase S8, subtilisin, Ser-active site PLAC
UniProtKB:Q069L0 917
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations