ZFIN is now using GRCz12tu for Genomic Data
Gene
ampd2b
- ID
- ZDB-GENE-070713-5
- Name
- adenosine monophosphate deaminase 2b
- Symbol
- ampd2b Nomenclature History
- Previous Names
-
- ampd2
- fb72d11
- wu:fb72d11 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable AMP deaminase activity. Predicted to be involved in AMP metabolic process and IMP biosynthetic process. Predicted to act upstream of or within purine ribonucleoside monophosphate biosynthetic process. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 63 and pontocerebellar hypoplasia type 9. Orthologous to human AMPD2 (adenosine monophosphate deaminase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 63 | Alliance | ?Spastic paraplegia 63, autosomal recessive | 615686 |
| pontocerebellar hypoplasia type 9 | Alliance | Pontocerebellar hypoplasia, type 9 | 615809 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Adenosine/AMP deaminase active site | AMP deaminase | Metal-dependent hydrolase |
|---|---|---|---|---|---|
| UniProtKB:B8JIS9 | InterPro | 756 | |||
| UniProtKB:A0A8M9QA40 | InterPro | 814 | |||
| UniProtKB:A0A8M3AV69 | InterPro | 830 | |||
| UniProtKB:A0A8M9QIZ0 | InterPro | 813 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ampd2b-201
(1)
|
Ensembl | 836 nt | ||
| mRNA |
ampd2b-202
(1)
|
Ensembl | 4,518 nt | ||
| mRNA |
ampd2b-203
(1)
|
Ensembl | 2,609 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers