Gene
st6galnac5a
- ID
- ZDB-GENE-070705-488
- Name
- ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5a
- Symbol
- st6galnac5a Nomenclature History
- Previous Names
-
- st6galnac5-r2 (1)
- si:dkey-70k13.1
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity. Predicted to be involved in ganglioside biosynthetic process and oligosaccharide metabolic process. Predicted to act upstream of or within lipid metabolic process and protein glycosylation. Predicted to be located in Golgi membrane. Is expressed in brain; gill; intestine; and testis. Orthologous to human ST6GALNAC5 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Yamakawa et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| tpl5Gt | Transgenic insertion | Unknown | Unknown | DNA |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Glycosyl transferase family 29 | GT29-like superfamiliy |
|---|---|---|---|---|
| UniProtKB:F1Q5Y4 | InterPro | 325 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
st6galnac5a-201
(1)
|
Ensembl | 1,161 nt | ||
| mRNA |
st6galnac5a-202
(1)
|
Ensembl | 975 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-226B21 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-70K13 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_686955 (1) | 5464 nt | ||
| Genomic | GenBank:BX469891 (1) | 175261 nt | ||
| Polypeptide | UniProtKB:F1Q5Y4 (1) | 325 aa |
- Yamakawa, N., Vanbeselaere, J., Chang, L.Y., Yu, S.Y., Ducrocq, L., Harduin-Lepers, A., Kurata, J., Aoki-Kinoshita, K.F., Sato, C., Khoo, K.H., Kitajima, K., Guerardel, Y. (2018) Systems glycomics of adult zebrafish identifies organ-specific sialylation and glycosylation patterns. Nature communications. 9:4647
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Balciuniene, J., Nagelberg, D., Walsh, K., Camerota, D., Georlette, D., Biemar, F., Bellipanni, G., and Balciunas, D. (2013) Efficient disruption of Zebrafish genes using a Gal4-containing gene trap. BMC Genomics. 14(1):619
- Vanbeselaere, J., Chang, L.Y., Harduin-Lepers, A., Fabre, E., Yamakawa, N., Slomianny, C., Biot, C., Khoo, K.H., and Guerardel, Y. (2012) Mapping the expressed glycome and glycosyltransferases of zebrafish liver cells as a relevant model system for glycosylation studies. Journal of Proteome Research. 11(4):2164-2177
- Harduin-Lepers, A. (2010) Comprehensive Analysis of sialyltransferases in vertebrate genomes.. Glycobiology. 2010:2:29-61
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