Gene
tnrc6bb.1
- ID
- ZDB-GENE-070705-475
- Name
- trinucleotide repeat containing adaptor 6Bb.1
- Symbol
- tnrc6bb.1 Nomenclature History
- Previous Names
-
- si:dkey-46g23.1
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to be involved in miRNA-mediated post-transcriptional gene silencing and positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Predicted to be located in cytoplasm. Predicted to be active in P-body and nucleoplasm. Human ortholog(s) of this gene implicated in subserous uterine fibroid and uterine fibroid. Orthologous to human TNRC6B (trinucleotide repeat containing adaptor 6B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa8537 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Global developmental delay with speech and behavioral abnormalities | 619243 |
1 - 1 of 1
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GW182 domain-containing protein | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | TNRC6, PABC binding domain |
|---|---|---|---|---|---|---|
| UniProtKB:E7F923 | InterPro | 1443 | ||||
| UniProtKB:A0A8M9QAP9 | InterPro | 1410 | ||||
| UniProtKB:A0A286YB96 | InterPro | 1472 |
1 - 3 of 3
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:dkey-46g23.1-201
(1)
|
Ensembl | 4,332 nt | ||
| mRNA |
si:dkey-46g23.1-202
(1)
|
Ensembl | 9,907 nt | ||
| mRNA |
si:dkey-46g23.1-203
(1)
|
Ensembl | 4,419 nt |
1 - 3 of 3
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-46G23 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_001332799 (1) | |||
| Genomic | GenBank:BX322654 (1) | 118113 nt | ||
| Polypeptide | UniProtKB:A0A286YB96 (1) | 1472 aa |