Gene
il17ra1a
- ID
- ZDB-GENE-070705-242
- Name
- interleukin 17 receptor A1a
- Symbol
- il17ra1a Nomenclature History
- Previous Names
-
- si:ch73-80e1.2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable interleukin-17 receptor activity. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in immunodeficiency 51. Orthologous to human IL17RA (interleukin 17 receptor A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Helal et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 51 | Alliance | Immunodeficiency 51 | 613953 |
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Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013568 | SEFIR domain |
| Domain | IPR032356 | Interleukin-17 receptor, fibronectin-III-like domain 1 |
| Family | IPR039465 | Interleukin-17 receptor-like |
| Homologous_superfamily | IPR038683 | Interleukin-17 receptor A/B, FnIII-like domain 1 superfamily |
| Homologous_superfamily | IPR043046 | Interleukin-17 receptor A/B, FnIII-like domain 2 superfamily |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Interleukin-17 receptor A/B, FnIII-like domain 1 superfamily | Interleukin-17 receptor A/B, FnIII-like domain 2 superfamily | Interleukin-17 receptor, fibronectin-III-like domain 1 | Interleukin-17 receptor-like | SEFIR domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:F2Z4X3 | InterPro | 782 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
il17ra1a-201
(1)
|
Ensembl | 2,940 nt | ||
| ncRNA |
il17ra1a-002
(1)
|
Ensembl | 768 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-80E1 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001100003 (1) | |||
| Genomic | GenBank:CT826375 (1) | 72299 nt | ||
| Polypeptide | UniProtKB:F2Z4X3 (1) | 782 aa |
- Lin, C., Tang, Y., Wang, Y., Zhang, J., Li, Y., Xu, S., Xia, B., Zhai, Q., Li, Y., Zhang, L., Liu, J. (2022) WhiB4 Is Required for the Reactivation of Persistent Infection of Mycobacterium marinum in Zebrafish. Microbiology spectrum. 10(2):e0044321
- Helal, M., Yan, C., Gong, Z. (2021) Stimulation of hepatocarcinogenesis by activated cholangiocytes via Il17a/f1 pathway in kras transgenic zebrafish model. Scientific Reports. 11:1372
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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