Gene

il17ra1a

ID

ZDB-GENE-070705-242

Name

interleukin 17 receptor A1a

Symbol

il17ra1a Nomenclature History

Previous Names

si:ch73-80e1.2 (1)

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have interleukin-17 receptor activity. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human IL17RA (interleukin 17 receptor A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Helal et al., 2021

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With il17ra1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
immunodeficiency 51	Alliance	Immunodeficiency 51	613953

Associated With il17ra1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR013568	SEFIR domain
Domain	IPR032356	Interleukin-17 receptor, fibronectin-III-like domain 1
Family	IPR039465	Interleukin-17 receptor-like
Homologous_superfamily	IPR038683	Interleukin-17 receptor A/B, FnIII-like domain 1 superfamily
Homologous_superfamily	IPR043046	Interleukin-17 receptor A/B, FnIII-like domain 2 superfamily

Domain Details Per Protein

Protein	Length	Interleukin-17 receptor A/B, FnIII-like domain 1 superfamily	Interleukin-17 receptor A/B, FnIII-like domain 2 superfamily	Interleukin-17 receptor, fibronectin-III-like domain 1	Interleukin-17 receptor-like	SEFIR domain
UniProtKB:F2Z4X3 InterPro	782

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	il17ra1a-201 (1) Ensembl	Havana	2940 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	il17ra1a-002 (1) Ensembl	Havana	768 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations