Gene

itpa

ID
ZDB-GENE-070705-218
Name
inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
Symbol
itpa Nomenclature History
Previous Names
  • si:ch73-18j6.1
  • si:dkey-19f21.1
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to enable nucleoside triphosphate diphosphatase activity. Predicted to be involved in nucleoside triphosphate catabolic process. Predicted to act upstream of or within nucleotide metabolic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); developmental and epileptic encephalopathy 35; hepatitis C; rheumatoid arthritis; and thrombocytopenia. Orthologous to human ITPA (inosine triphosphatase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With itpa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
developmental and epileptic encephalopathy 35 Alliance Developmental and epileptic encephalopathy 35 616647
[Inosine triphosphatase deficiency] 613850
Associated With itpa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002637 Ham1-like protein
Family IPR027502 Inosine triphosphate pyrophosphatase
Homologous_superfamily IPR029001 Inosine triphosphate pyrophosphatase-like
Domain Details Per Protein
Protein Length Ham1-like protein Inosine triphosphate pyrophosphatase Inosine triphosphate pyrophosphatase-like
UniProtKB:A5WVX0 203
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations