Gene

prlrb

ID
ZDB-GENE-070705-155
Name
prolactin receptor b
Symbol
prlrb Nomenclature History
Previous Names
  • si:ch211-261c8.2 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have cytokine binding activity; peptide hormone binding activity; and prolactin receptor activity. Predicted to be involved in prolactin signaling pathway. Predicted to localize to external side of plasma membrane and receptor complex. Human ortholog(s) of this gene implicated in hyperprolactinemia. Is expressed in gill and pronephros. Orthologous to human PRLR (prolactin receptor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prlrb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Hyperprolactinemia 615555
Multiple fibroadenomas of the breast 615554
Associated With prlrb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003961 Fibronectin type III
Domain IPR015152 Growth hormone/erythropoietin receptor, ligand binding
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Domain Details Per Protein
Protein Length Fibronectin type III Fibronectin type III superfamily Growth hormone/erythropoietin receptor, ligand binding Immunoglobulin-like fold
UniProtKB:A8WH90 450
UniProtKB:A0A8M2BCV8 454
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations