Gene

lyst

ID
ZDB-GENE-070702-1
Name
lysosomal trafficking regulator
Symbol
lyst Nomenclature History
Previous Names
  • si:ch211-30i2.1
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Human ortholog(s) of this gene implicated in Chediak-Higashi syndrome. Orthologous to human LYST (lysosomal trafficking regulator).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Kim et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lyst Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Chediak-Higashi syndrome Alliance Chediak-Higashi syndrome 214500
1 - 1 of 1
Associated With lyst Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR000409 BEACH domain
Domain IPR023362 PH-BEACH domain
Family IPR050865 BEACH Domain-Containing
Homologous_superfamily IPR011993 PH-like domain superfamily
1 - 5 of 9 Show all
Domain Details Per Protein
Protein Additional Resources Length BEACH domain BEACH Domain-Containing BEACH domain superfamily PH-BEACH domain PH-like domain superfamily WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A8M6Z3Z4 InterPro 3826
UniProtKB:A0A8M6Z2E9 InterPro 3886
UniProtKB:A0A8M9PU84 InterPro 3832
UniProtKB:A0A8M3AZH9 InterPro 3832
UniProtKB:A0AB32TLB9 InterPro 3886
1 - 5 of 6 Show all
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA lyst-201 (1) Ensembl 8,001 nt
mRNA lyst-202 (1) Ensembl 7,983 nt
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations