Gene

cdk5rap1

ID

ZDB-GENE-070424-90

Name

CDK5 regulatory subunit associated protein 1

Symbol

cdk5rap1 Nomenclature History

Previous Names

zgc:162738

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have N6-isopentenyladenosine methylthiotransferase activity. Predicted to be involved in negative regulation of cyclin-dependent protein serine/threonine kinase activity. Predicted to localize to cytosol and mitochondrion. Orthologous to human CDK5RAP1 (CDK5 regulatory subunit associated protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cdk5rap1 Human Ortholog

No data available

Associated With cdk5rap1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020612	Methylthiotransferase, conserved site
Domain	IPR002792	TRAM domain
Domain	IPR006638	Elp3/MiaA/NifB-like, radical SAM core domain
Domain	IPR007197	Radical SAM
Domain	IPR013848	Methylthiotransferase, N-terminal
Family	IPR005839	Methylthiotransferase
Family	IPR006463	tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB
Homologous_superfamily	IPR023404	Radical SAM, alpha/beta horseshoe
Homologous_superfamily	IPR038135	Methylthiotransferase, N-terminal domain superfamily

Domain Details Per Protein

Protein	Length	Elp3/MiaA/NifB-like, radical SAM core domain	Methylthiotransferase	Methylthiotransferase, conserved site	Methylthiotransferase, N-terminal	Methylthiotransferase, N-terminal domain superfamily	Radical SAM	Radical SAM, alpha/beta horseshoe	TRAM domain	tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB
UniProtKB:A8WGJ0 InterPro	577
UniProtKB:A0A8M9QLN1 InterPro	404

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	cdk5rap1-201 (1) Ensembl	Havana	2122 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	cdk5rap1-002 (1) Ensembl	Havana	1541 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations