Gene

tasp1

ID
ZDB-GENE-070424-242
Name
taspase, threonine aspartase, 1
Symbol
tasp1 Nomenclature History
Previous Names
  • si:dkey-38k3.3
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to enable threonine-type endopeptidase activity. Acts upstream of or within brain development and cartilage development. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human TASP1 (taspase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Riedhammer et al., 2022
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la027443TgTransgenic insertionUnknownUnknownDNA
s4006Allele with one deletionUnknownUnknownCRISPR
sa22345Allele with one point mutationUnknownSplice SiteENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-tasp1Riedhammer et al., 2022
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Human Disease
Associated With tasp1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Suleiman-El-Hattab syndrome 618950
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Associated With tasp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000246 Peptidase T2, asparaginase 2
Family IPR037464 Threonine aspartase 1
Homologous_superfamily IPR029055 Nucleophile aminohydrolases, N-terminal
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Domain Details Per Protein
Protein Additional Resources Length Nucleophile aminohydrolases, N-terminal Peptidase T2, asparaginase 2 Threonine aspartase 1
UniProtKB:A0A2R8QBP8 InterPro 409
UniProtKB:A5PMQ0 InterPro 422
UniProtKB:A0A8M2B3S9 InterPro 343
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 13
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tasp1-201 (1) Ensembl 6,088 nt
mRNA tasp1-203 (1) Ensembl 1,230 nt
ncRNA ottdart00000061593 (1) Ensembl 905 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-153M11ZFIN Curated Data
Contained inBACDKEY-38K3ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanTASP120
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseTasp12
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
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