Gene

edar

ID
ZDB-GENE-070117-2062
Name
ectodysplasin A receptor
Symbol
edar Nomenclature History
Previous Names
  • finless (1)
  • fls (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have signaling receptor activity. Involved in dermal bone morphogenesis and fin development. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in ectodermal dysplasia 10A and ectodermal dysplasia 10B. Is expressed in several structures, including epidermal cell; integument; mouth; pectoral fin skeleton; and pelvic fin bud. Orthologous to human EDAR (ectodysplasin A receptor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from 6 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With edar Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
ectodermal dysplasia 10A Alliance Ectodermal dysplasia 10A, hypohidrotic/hair/nail type, autosomal dominant 129490
ectodermal dysplasia 10B Alliance Ectodermal dysplasia 10B, hypohidrotic/hair/tooth type, autosomal recessive 224900
[Hair morphology 1, hair thickness] 612630
Associated With edar Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR034052 Tumor necrosis factor receptor EDAR, N-terminal
Homologous_superfamily IPR011029 Death-like domain superfamily
Domain Details Per Protein
Protein Length Death-like domain superfamily Tumor necrosis factor receptor EDAR, N-terminal
UniProtKB:B0YIF2 459
UniProtKB:A0A0R4IGE7 460
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations