ZFIN is now using GRCz12tu for Genomic Data
Gene
napbb
- ID
- ZDB-GENE-070112-2132
- Name
- N-ethylmaleimide-sensitive factor attachment protein, beta b
- Symbol
- napbb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable soluble NSF attachment protein activity. Acts upstream of or within photoreceptor cell maintenance. Predicted to be located in membrane. Predicted to be part of synaptobrevin 2-SNAP-25-syntaxin-1a complex. Predicted to be active in terminal bouton. Is expressed in head; tail bud; telencephalon; visual system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 107. Orthologous to human NAPB (NSF attachment protein beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 107 | Alliance | Developmental and epileptic encephalopathy 107 | 620033 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | NSF attachment protein | Tetratricopeptide-like helical domain superfamily |
|---|---|---|---|---|
| UniProtKB:A0A8M9P2Q3 | InterPro | 182 | ||
| UniProtKB:A1L245 | InterPro | 295 | ||
| UniProtKB:F1Q9P4 | InterPro | 295 | ||
| UniProtKB:A0AB32T6Y9 | InterPro | 217 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance