Gene
tnxba
- ID
- ZDB-GENE-070103-5
- Name
- tenascin XBa
- Symbol
- tnxba Nomenclature History
- Previous Names
-
- tnxb
- si:dkey-8k3.1
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to be involved in neuron projection development and regulation of cell adhesion. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome; Ehlers-Danlos syndrome classic-like 1; and vesicoureteral reflux. Orthologous to human TNXB (tenascin XB).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ehlers-Danlos syndrome classic-like 1 | Alliance | Ehlers-Danlos syndrome, classic-like, 1 | 606408 |
| vesicoureteral reflux | Alliance | Vesicoureteral reflux 8 | 615963 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020837 | Fibrinogen, conserved site |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR002181 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain |
| Domain | IPR003961 | Fibronectin type III |
| Family | IPR050991 | Extracellular Matrix Regulatory Proteins |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014716 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 |
| Homologous_superfamily | IPR036056 | Fibrinogen-like, C-terminal |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | EGF-like domain | Extracellular Matrix Regulatory Proteins | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 | Fibrinogen, conserved site | Fibrinogen-like, C-terminal | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin-like fold |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9P891 | InterPro | 2285 | |||||||||
| UniProtKB:A0A8M9PMY3 | InterPro | 851 | |||||||||
| UniProtKB:A0A8M9PDJ3 | InterPro | 2116 |
Interactions and Pathways
No data available
Plasmids
No data available