Gene

g6pc3

ID
ZDB-GENE-061215-19
Name
glucose-6-phosphatase catalytic subunit 3
Symbol
g6pc3 Nomenclature History
Previous Names
  • zgc:158425
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to enable glucose-6-phosphatase activity. Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in membrane. Is expressed in ventral wall of dorsal aorta. Human ortholog(s) of this gene implicated in severe congenital neutropenia 4. Orthologous to human G6PC3 (glucose-6-phosphatase catalytic subunit 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Zhang et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Zhang et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With g6pc3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
severe congenital neutropenia 4 Alliance Dursun syndrome 612541
severe congenital neutropenia 4 Alliance Neutropenia, severe congenital 4, autosomal recessive 612541
Associated With g6pc3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase
Family IPR016275 Glucose-6-phosphatase
Homologous_superfamily IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
Domain Details Per Protein
Protein Length Glucose-6-phosphatase Phosphatidic acid phosphatase type 2/haloperoxidase Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
UniProtKB:F1QI88 339
UniProtKB:A1A5Z0 339
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations