Gene

tyrobp

ID
ZDB-GENE-061130-2
Name
transmembrane immune signaling adaptor TYROBP
Symbol
tyrobp Nomenclature History
Previous Names
  • dap12 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have signaling receptor binding activity. Involved in phosphatidylinositol 3-kinase signaling. Predicted to localize to cell surface. Is expressed in liver; lymphocyte; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Nasu-Hakola disease. Orthologous to human TYROBP (transmembrane immune signaling adaptor TYROBP).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tyrobp Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Nasu-Hakola disease Alliance Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1 221770
Associated With tyrobp Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR026200 TYRO protein tyrosine kinase-binding protein
Domain Details Per Protein
Protein Length TYRO protein tyrosine kinase-binding protein
UniProtKB:F1QN44 115
UniProtKB:A6Y956 115
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations