Gene
lrrc28
- ID
- ZDB-GENE-061128-1
- Name
- leucine rich repeat containing 28
- Symbol
- lrrc28 Nomenclature History
- Previous Names
-
- wu:fk49g08
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to be involved in intracellular signal transduction. Orthologous to human LRRC28 (leucine rich repeat containing 28).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR055414 | Disease resistance R13L4/SHOC-2-like, LRR domain |
| Family | IPR050216 | Leucine-rich repeat domain-containing protein |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
| Repeat | IPR001611 | Leucine-rich repeat |
| Repeat | IPR003591 | Leucine-rich repeat, typical subtype |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Disease resistance R13L4/SHOC-2-like, LRR domain | Leucine-rich repeat | Leucine-rich repeat domain-containing protein | Leucine-rich repeat domain superfamily | Leucine-rich repeat, typical subtype |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8N7UQL8 | InterPro | 366 | |||||
| UniProtKB:E7FBW4 | InterPro | 366 | |||||
| UniProtKB:A0AB32TF24 | InterPro | 365 |
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- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
lrrc28-201
(1)
|
Ensembl | 4,493 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-134B16 | ZFIN Curated Data | |
| Encodes | EST | fk49g08 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_678142 (1) | 4231 nt | ||
| Genomic | GenBank:BX088692 (1) | 210074 nt | ||
| Polypeptide | UniProtKB:A0A8N7UQL8 (1) | 366 aa |
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Cañestro, C., Catchen, J.M., Rodriguez-Mari, A., Yokoi, H., and Postlethwait, J.H. (2009) Consequences of lineage-specific gene loss on functional evolution of surviving paralogs: ALDH1A and retinoic acid signaling in vertebrate genomes. PLoS Genetics. 5(5):e1000496
- Lo, J., Lee, S., Xu, M., Liu, F., Ruan, H., Eun, A., He, Y., Ma, W., Wang, W., Wen, Z., and Peng, J. (2003) 15,000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Genome research. 13(3):455-466
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