Gene
tbc1d32
- ID
- ZDB-GENE-061106-5
- Name
- TBC1 domain family, member 32
- Symbol
- tbc1d32 Nomenclature History
- Previous Names
-
- bromi (1)
- si:dkey-233p4.1
- si:dkey233p4.1
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Acts upstream of or within axoneme assembly. Predicted to be located in cilium and cytoplasm. Orthologous to human TBC1D32 (TBC1 domain family member 32).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Ko et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Allele | Type | Localization | Consequence | Mutagen | Supplier |
---|---|---|---|---|---|
sa16300 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa16562 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa29433 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa43510 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
sa45715 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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Targeting Reagent | Created Alleles | Citations |
---|---|---|
MO1-tbc1d32 | N/A | Ko et al., 2010 |
MO2-tbc1d32 | N/A | Ko et al., 2010 |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | BROMI, C-terminal Rab TBC-like domain | BROMI, middle region | BROMI, N-terminal domain | PHAF1/Protein broad-minded | Rab-GAP-TBC domain superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:Q5RHR6 | InterPro | 1298 | |||||
UniProtKB:A0A8M9PPI1 | InterPro | 1300 |
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Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
tbc1d32-201
(1)
|
Ensembl | 3,897 nt | ||
mRNA |
tbc1d32-202
(1)
|
Ensembl | 4,193 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | CH211-172B19 | ZFIN Curated Data | |
Contained in | BAC | DKEY-233P4 | ZFIN Curated Data | |
Contained in | Fosmid | CH1073-265L12 | ZFIN Curated Data |
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Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001100023 (1) | 3897 nt | ||
Genomic | GenBank:BX470071 (1) | 154409 nt | ||
Polypeptide | UniProtKB:A0A8M9PPI1 (1) | 1300 aa |
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Ko, H.W., Norman, R.X., Tran, J., Fuller, K.P., Fukuda, M., and Eggenschwiler, J.T. (2010) Broad-Minded Links Cell Cycle-Related Kinase to Cilia Assembly and Hedgehog Signal Transduction. Developmental Cell. 18(2):237-247
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