Gene
bcl11ab
- ID
- ZDB-GENE-061009-4
- Name
- BCL11 transcription factor A b
- Symbol
- bcl11ab Nomenclature History
- Previous Names
-
- si:ch211-127m10.2
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within brain development. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autism spectrum disorder; beta thalassemia; schizophrenia; and sickle cell anemia. Orthologous to human BCL11A (BCL11 transcription factor A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Ramachandran et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Bagheri et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Dias-Logan syndrome | 617101 |
1 - 1 of 1
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | CTCF-like, C2H2 zinc finger | Developmental and Hematopoietic Transcription Factors | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|
| UniProtKB:A2BE84 | InterPro | 776 | ||||
| UniProtKB:A0A8M9PZU7 | InterPro | 592 |
1 - 2 of 2
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
bcl11ab-201
(1)
|
Ensembl | 2,605 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available