Gene

mmp16b

ID
ZDB-GENE-061009-22
Name
matrix metallopeptidase 16b (membrane-inserted)
Symbol
mmp16b Nomenclature History
Previous Names
  • si:ch211-261f3.1
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process; extracellular matrix organization; and skeletal system development. Predicted to be located in membrane. Predicted to be active in extracellular space and plasma membrane. Orthologous to human MMP16 (matrix metallopeptidase 16).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Quick et al., 2012
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Thyme et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
a302Allele with one deletionUnknownUnknownCRISPR
la014966TgTransgenic insertionUnknownUnknownDNA
sa6824Allele with one point mutationUnknownPremature StopENU
sa31251Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-mmp16bThyme et al., 2019
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Human Disease
Associated With mmp16b Human Ortholog
No data available
Associated With mmp16b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR021158 Peptidase M10A, cysteine switch, zinc binding site
Conserved_site IPR018486 Hemopexin, conserved site
Domain IPR000585 Hemopexin-like domain
Domain IPR001818 Peptidase M10, metallopeptidase
Domain IPR002477 Peptidoglycan binding-like
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Domain Details Per Protein
Protein Additional Resources Length Hemopexin, conserved site Hemopexin-like domain Hemopexin-like domain superfamily Hemopexin-like repeats Metallopeptidase, catalytic domain superfamily Peptidase M10A Peptidase M10A, catalytic domain Peptidase M10A, cysteine switch, zinc binding site Peptidase M10A, matrix metallopeptidase, C-terminal Peptidase M10, metallopeptidase Peptidase, metallopeptidase Peptidoglycan binding-like PGBD-like superfamily
UniProtKB:F1R8N4 InterPro 618
UniProtKB:A0A8N7TFK6 InterPro 613
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 2
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mmp16b-201 (1) Ensembl 1,785 nt
mRNA mmp16b-202 (1) Ensembl 3,087 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-261F3ZFIN Curated Data
Contained inBACDKEY-283M16ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanMMP168
Amino acid sequence comparison (2)
MouseMmp164
Amino acid sequence comparison (1)
Citations
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