Gene
mbnl1
- ID
- ZDB-GENE-060929-704
- Name
- muscleblind-like splicing regulator 1
- Symbol
- mbnl1 Nomenclature History
- Previous Names
-
- zgc:153954
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in nucleus. Predicted to be active in cytoplasm and nucleoplasm. Is expressed in several structures, including blood; gonad; heart; nervous system; and swim bladder. Used to study myotonic disease. Orthologous to human MBNL1 (muscleblind like splicing regulator 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Hinman et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Human Disease | Fish | Conditions | Citations |
---|---|---|---|
myotonic disease | mbnl1b1358/b1358 | standard conditions | Hinman et al., 2021 |
myotonic disease | mbnl1b1359/b1359 | standard conditions | Hinman et al., 2021 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Muscleblind-like, CCCH zinc finger | Zinc finger, CCCH-type |
---|---|---|---|---|
UniProtKB:A5YC46 | InterPro | 412 | ||
UniProtKB:Q08BY7 | InterPro | 303 | ||
UniProtKB:A0A8M1NE31 | InterPro | 412 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
mbnl1-201
(1)
|
Ensembl | 1,894 nt | ||
mRNA |
mbnl1-202
(1)
|
Ensembl | 1,912 nt | ||
mRNA |
mbnl1-203
(1)
|
Ensembl | 1,948 nt | ||
mRNA |
mbnl1-204
(1)
|
Ensembl | 1,883 nt | ||
mRNA |
mbnl1-205
(1)
|
Ensembl | 2,124 nt | ||
mRNA |
mbnl1-206
(1)
|
Ensembl | 1,858 nt | ||
mRNA |
mbnl1-207
(1)
|
Ensembl | 912 nt | ||
mRNA |
mbnl1-208
(1)
|
Ensembl | 2,178 nt |
Interactions and Pathways
No data available
Plasmids
No data available