Gene

mtfmt

ID
ZDB-GENE-060929-120
Name
mitochondrial methionyl-tRNA formyltransferase
Symbol
mtfmt Nomenclature History
Previous Names
  • zgc:152651
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable methionyl-tRNA formyltransferase activity. Predicted to be involved in conversion of methionyl-tRNA to N-formyl-methionyl-tRNA. Predicted to act upstream of or within translation. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 15 and nuclear type mitochondrial complex I deficiency 27. Orthologous to human MTFMT (mitochondrial methionyl-tRNA formyltransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mtfmt Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
combined oxidative phosphorylation deficiency 15 Alliance Combined oxidative phosphorylation deficiency 15 614947
nuclear type mitochondrial complex I deficiency 27 Alliance Mitochondrial complex I deficiency, nuclear type 27 618248
Associated With mtfmt Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002376 Formyl transferase, N-terminal
Domain IPR005793 Formyl transferase, C-terminal
Domain IPR041711 Methionyl-tRNA formyltransferase, N-terminal domain
Family IPR005794 Methionyl-tRNA formyltransferase
Homologous_superfamily IPR036477 Formyl transferase, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Formyl transferase, C-terminal Formyl transferase, N-terminal Formyl transferase, N-terminal domain superfamily Methionyl-tRNA formyltransferase Methionyl-tRNA formyltransferase, N-terminal domain
UniProtKB:A5PL71 390
UniProtKB:A8E5A7 390
UniProtKB:F1QJ58 390
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations