ZFIN is now using GRCz12tu for Genomic Data
Gene

mosmob

ID
ZDB-GENE-060929-1030
Name
modulator of smoothened b
Symbol
mosmob Nomenclature History
Previous Names
  • zgc:153595
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Acts upstream of or within cranial skeletal system development. Predicted to be located in plasma membrane. Predicted to be active in Golgi apparatus and ciliary membrane. Is expressed in head mesenchyme; mesenchyme; neural tube; and optic vesicle. Orthologous to human MOSMO (modulator of smoothened).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Camacho-Macorra et al., 2021
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
cbm21Allele with one deletionExon 2UnknownCRISPR
sa22045Allele with one point mutationUnknownPremature StopENU
1 - 2 of 2
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-mosmobCamacho-Macorra et al., 2021
1 - 1 of 1
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Human Disease
Associated With mosmob Human Ortholog
No data available
Associated With mosmob Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR037663 Modulator of smoothened protein
1 - 1 of 1
Domain Details Per Protein
Protein Additional Resources Length Modulator of smoothened protein
UniProtKB:Q0D289 InterPro 167
1 - 1 of 1
Transcripts
Genome Browsers
Genome Assembly: GRCz11Chromosome: 12
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mosmob-201 (1) Ensembl 1,918 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-389D14ZFIN Curated Data
EncodescDNAMGC:153595ZFIN Curated Data
1 - 2 of 2
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Sequences
Genome Browsers
Genome Assembly: GRCz12tuChromosome: 12
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanMOSMO16
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseMosmo7
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
1 - 3 of 3
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