Gene
ifi27.2
- ID
- ZDB-GENE-060901-4
- Name
- interferon alpha inducible protein 27.2
- Symbol
- ifi27.2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable molecular adaptor activity. Predicted to be involved in intrinsic apoptotic signaling pathway. Predicted to be located in membrane. Predicted to be active in mitochondrial membrane. Orthologous to human IFI27 (interferon alpha inducible protein 27) and IFI27L1 (interferon alpha inducible protein 27 like 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Rajshekar et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | IFI6/IFI27-like domain superfamily | Interferon alpha-inducible protein IFI6/IFI27-like |
---|---|---|---|---|
UniProtKB:F6NVZ1 | InterPro | 96 |
1 - 1 of 1
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
zgc:152791-201
(1)
|
Ensembl | 803 nt | ||
mRNA |
zgc:152791-202
(1)
|
Ensembl | 842 nt | ||
mRNA |
zgc:152791-203
(1)
|
Ensembl | 842 nt | ||
mRNA |
zgc:152791-204
(1)
|
Ensembl | 842 nt |
1 - 4 of 4
Interactions and Pathways
No data available
Plasmids
No data available
No data available
Relationship | Marker Type | Marker | Accession Numbers | Citations |
---|---|---|---|---|
Contained in | BAC | DKEY-188I13 | ZFIN Curated Data | |
Encodes | cDNA | MGC:123067 | ZFIN Curated Data | |
Encodes | cDNA | MGC:152791 | ZFIN Curated Data | |
Encodes | cDNA | MGC:158560 | ZFIN Curated Data |
1 - 4 of 4
Show
Type | Accession # | Sequence | Length (nt/aa) | Analysis |
---|---|---|---|---|
RNA | RefSeq:NM_001291934 (1) | 967 nt | ||
Genomic | GenBank:BX005106 (1) | 216863 nt | ||
Polypeptide | UniProtKB:F6NVZ1 (1) | 96 aa |
- Demin, K.A., Lakstygal, A.M., Krotova, N.A., Masharsky, A., Tagawa, N., Chernysh, M.V., Ilyin, N.P., Taranov, A.S., Galstyan, D.S., Derzhavina, K.A., Levchenko, N.A., Kolesnikova, T.O., Mor, M.S., Vasyutina, M.L., Efimova, E.V., Katolikova, N., Prjibelski, A.D., Gainetdinov, R.R., de Abreu, M.S., Amstislavskaya, T.G., Strekalova, T., Kalueff, A.V. (2020) Understanding complex dynamics of behavioral, neurochemical and transcriptomic changes induced by prolonged chronic unpredictable stress in zebrafish. Scientific Reports. 10:19981
- Levraud, J.P., Jouneau, L., Briolat, V., Laghi, V., Boudinot, P. (2019) IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity. Journal of immunology (Baltimore, Md. : 1950). 203(12):3361-3373
- Rajshekar, S., Yao, J., Arnold, P.K., Payne, S.G., Zhang, Y., Bowman, T.V., Schmitz, R.J., Edwards, J.R., Goll, M. (2018) Pericentromeric hypomethylation elicits an interferon response in an animal model of ICF syndrome. eLIFE. 7:
- Ribas, L., Vanezis, K., Imués, M.A., Piferrer, F. (2017) Treatment with a DNA methyltransferase inhibitor feminizes zebrafish and induces long-term expression changes in the gonads. Epigenetics & chromatin. 10:59
- Filiano, A.J., Xu, Y., Tustison, N.J., Marsh, R.L., Baker, W., Smirnov, I., Overall, C.C., Gadani, S.P., Turner, S.D., Weng, Z., Peerzade, S.N., Chen, H., Lee, K.S., Scott, M.M., Beenhakker, M.P., Litvak, V., Kipnis, J. (2016) Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour. Nature. 535:425-9
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Briolat, V., Jouneau, L., Carvalho, R., Palha, N., Langevin, C., Herbomel, P., Schwartz, O., Spaink, H.P., Levraud, J.P., Boudinot, P. (2014) Contrasted Innate Responses to Two Viruses in Zebrafish: Insights into the Ancestral Repertoire of Vertebrate IFN-Stimulated Genes. Journal of immunology (Baltimore, Md. : 1950). 192:4328-41
- López-Muñoz, A., Sepulcre, M.P., Roca, F.J., Figueras, A., Meseguer, J., and Mulero, V. (2011) Evolutionary conserved pro-inflammatory and antigen presentation functions of zebrafish IFNγ revealed by transcriptomic and functional analysis. Molecular immunology. 48(9-10):1073-1083
- Jima, D.D., Shah, R.N., Orcutt, T.M., Joshi, D., Law, J.M., Litman, G.W., Trede, N.S., and Yoder, J.A. (2009) Enhanced transcription of complement and coagulation genes in the absence of adaptive immunity. Molecular immunology. 46(7):1505-1516
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
1 - 10 of 10
Show