Gene
nprl2
- ID
- ZDB-GENE-060825-93
- Name
- NPR2 like, GATOR1 complex subunit
- Symbol
- nprl2 Nomenclature History
- Previous Names
-
- im:6900399
- tusc4
- zgc:153630
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to be involved in cellular response to starvation; negative regulation of TOR signaling; and regulation of autophagy. Predicted to localize to GATOR1 complex. Human ortholog(s) of this gene implicated in focal epilepsy. Orthologous to human NPRL2 (NPR2 like, GATOR1 complex subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6900399 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial focal epilepsy with variable foci 2 | Alliance | Epilepsy, familial focal, with variable foci 2 | 617116 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR009348 | Nitrogen permease regulator 2-like |
Domain Details Per Protein
| Protein | Length | Nitrogen permease regulator 2-like |
|---|---|---|
|
UniProtKB:Q0P403
|
379 |
Interactions and Pathways
No data available
Plasmids
No data available