ZFIN is now using GRCz12tu for Genomic Data
Gene

nptx2a

ID
ZDB-GENE-060707-1
Name
neuronal pentraxin 2a
Symbol
nptx2a Nomenclature History
Previous Names
  • nptx2
  • narp (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Acts upstream of or within regulation of glutamatergic synaptic transmission. Is expressed in nervous system. Orthologous to human NPTX2 (neuronal pentraxin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Elbaz et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
biu6Allele with one insertionExon 1Premature StopTALEN
sa12556Allele with one point mutationUnknownSplice SiteENU
1 - 2 of 2
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
TALEN1-nptx2a (3)
1 - 1 of 1
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Human Disease
Associated With nptx2a Human Ortholog
No data available
Associated With nptx2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR030476 Pentaxin, conserved site
Family IPR001759 Pentraxin-related
Family IPR051360 Neuronal Pentraxin and Related
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
1 - 4 of 4
Domain Details Per Protein
Protein Additional Resources Length Concanavalin A-like lectin/glucanase domain superfamily Neuronal Pentraxin and Related Pentaxin, conserved site Pentraxin-related
UniProtKB:D2D0C1 InterPro 433
UniProtKB:A8E4K4 InterPro 432
UniProtKB:A0A8M6Z4G4 InterPro 235
UniProtKB:A0A8M3AR04 InterPro 234
UniProtKB:A0A8M2BBR8 InterPro 434
1 - 5 of 5
Transcripts
Genome Browsers
Genome Assembly: GRCz11Chromosome: 3
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nptx2a-201 (1) Ensembl 1,905 nt
mRNA nptx2a-202 (1) Ensembl 2,032 nt
mRNA nptx2a-203 (1) Ensembl 609 nt
mRNA nptx2a-204 (1) Ensembl 1,302 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Construct Regulatory Region Coding Sequence Species Tg Lines Citations
Tg(nptx2:GAL4-VP16)
  • nptx2a
  • Danio rerio
2 (13)
1 - 1 of 1
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Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-151L1ZFIN Curated Data
EncodescDNAMGC:136687ZFIN Curated Data
1 - 2 of 2
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Sequences
Genome Browsers
Genome Assembly: GRCz12tuChromosome: 3
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanNPTX27
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseNptx25
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
1 - 8 of 8
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