ZFIN is now using GRCz12tu for Genomic Data
Gene
npr3
- ID
- ZDB-GENE-060531-91
- Name
- natriuretic peptide receptor 3
- Symbol
- npr3 Nomenclature History
- Previous Names
-
- im:7138418
- si:dkey-199l1.2 (1)
- zgc:158440
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable natriuretic peptide receptor activity and peptide hormone binding activity. Acts upstream of or within cardiac muscle cell proliferation. Predicted to be located in membrane. Is expressed in several structures, including heart; hypochord; nervous system; neural tube; and renal system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human NPR3 (natriuretic peptide receptor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7138418 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Becker et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Boudin-Mortier syndrome | 619543 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Adenylyl cyclase class-4/guanylyl cyclase | Atrial Natriuretic Peptide Clearance Receptor | Periplasmic binding protein-like I | Receptor, ligand binding region |
|---|---|---|---|---|---|---|
| UniProtKB:A2RUY7 | InterPro | 472 | ||||
| UniProtKB:A0A2R8RSJ1 | InterPro | 503 | ||||
| UniProtKB:A0A8M1NFL0 | InterPro | 502 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers