Gene
stim1b
- ID
- ZDB-GENE-060531-4
- Name
- stromal interaction molecule 1b
- Symbol
- stim1b Nomenclature History
- Previous Names
-
- stim1
- si:ch211-112l17.2
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable calcium channel regulator activity and calcium ion binding activity. Predicted to be involved in intracellular calcium ion homeostasis and store-operated calcium entry. Predicted to act upstream of or within monoatomic ion transport. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum and plasma membrane. Is expressed in several structures, including brain; head; liver; pleuroperitoneal region; and skeletal muscle. Human ortholog(s) of this gene implicated in Stormorken syndrome; gastrointestinal system cancer (multiple); immunodeficiency 10; lung cancer; and tubular aggregate myopathy 1. Orthologous to human STIM1 (stromal interaction molecule 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 10 | Alliance | Immunodeficiency 10 | 612783 |
| Stormorken syndrome | Alliance | Stormorken syndrome | 185070 |
| tubular aggregate myopathy 1 | Alliance | Myopathy, tubular aggregate, 1 | 160565 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily | Stromal interaction molecule | Stromal interaction molecule, Orai1-activating region |
|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IAT9 | InterPro | 668 | ||||
| UniProtKB:F1R6G6 | InterPro | 641 | ||||
| UniProtKB:A0A8M1P2M0 | InterPro | 642 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
stim1b-201
(1)
|
Ensembl | 2,120 nt | ||
| mRNA |
stim1b-202
(1)
|
Ensembl | 2,575 nt |
Interactions and Pathways
No data available
Plasmids
No data available