Gene

stim1b

ID
ZDB-GENE-060531-4
Name
stromal interaction molecule 1b
Symbol
stim1b Nomenclature History
Previous Names
  • stim1
  • si:ch211-112l17.2
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to enable calcium channel regulator activity and calcium ion binding activity. Predicted to be involved in intracellular calcium ion homeostasis and store-operated calcium entry. Predicted to act upstream of or within monoatomic ion transport. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum and plasma membrane. Is expressed in several structures, including brain; head; liver; pleuroperitoneal region; and skeletal muscle. Human ortholog(s) of this gene implicated in Stormorken syndrome; gastrointestinal system cancer (multiple); immunodeficiency 10; lung cancer; and tubular aggregate myopathy 1. Orthologous to human STIM1 (stromal interaction molecule 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la014058TgTransgenic insertionUnknownUnknownDNA
la021963TgTransgenic insertionUnknownUnknownDNA
la021964TgTransgenic insertionUnknownUnknownDNA
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Sequence Targeting Reagents
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Human Disease
Associated With stim1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency 10 Alliance Immunodeficiency 10 612783
Stormorken syndrome Alliance Stormorken syndrome 185070
tubular aggregate myopathy 1 Alliance Myopathy, tubular aggregate, 1 160565
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Associated With stim1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001660 Sterile alpha motif domain
Domain IPR032393 Stromal interaction molecule, Orai1-activating region
Family IPR037608 Stromal interaction molecule
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
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Domain Details Per Protein
Protein Additional Resources Length Sterile alpha motif domain Sterile alpha motif/pointed domain superfamily Stromal interaction molecule Stromal interaction molecule, Orai1-activating region
UniProtKB:A0A0R4IAT9 InterPro 668
UniProtKB:F1R6G6 InterPro 641
UniProtKB:A0A8M1P2M0 InterPro 642
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 21
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA stim1b-201 (1) Ensembl 2,120 nt
mRNA stim1b-202 (1) Ensembl 2,575 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-112L17ZFIN Curated Data
Contained inBACDKEY-22F5ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanSTIM111
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseStim17
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
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