Gene
ptger4b
- ID
- ZDB-GENE-060531-102
- Name
- prostaglandin E receptor 4 (subtype EP4) b
- Symbol
- ptger4b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Enables prostaglandin E receptor activity. Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; cellular response to prostaglandin E stimulus; and negative regulation of inflammatory response. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including germ ring; intermediate cell mass of mesoderm; pleuroperitoneal region; trunk; and trunk neural crest. Human ortholog(s) of this gene implicated in ankylosing spondylitis; arteriosclerosis; and ulcerative colitis. Orthologous to human PTGER4 (prostaglandin E receptor 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Prostaglandin DP receptor | Prostanoid EP4 receptor | Prostanoid receptor |
|---|---|---|---|---|---|---|---|
| UniProtKB:A3QK20 | InterPro | 497 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptger4b-201
(1)
|
Ensembl | 1,494 nt |
Interactions and Pathways
No data available
Plasmids
No data available