Gene
kiss1rb
- ID
- ZDB-GENE-060526-54
- Name
- KISS1 receptor b
- Symbol
- kiss1rb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Enables neuropeptide receptor activity. Acts upstream of or within positive regulation of DNA-templated transcription. Located in cell surface; cytoplasm; and nucleus. Is expressed in several structures, including brain; fat cell; head; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in central precocious puberty 1; hypogonadism; and hypogonadotropic hypogonadism 8 with or without anosmia. Orthologous to human KISS1R (KISS1 receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| central precocious puberty 1 | Alliance | ?Precocious puberty, central, 1 | 176400 |
| hypogonadotropic hypogonadism 8 with or without anosmia | Alliance | Hypogonadotropic hypogonadism 8 with or without anosmia | 614837 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | KiSS-1 peptide receptor |
|---|---|---|---|---|---|
| UniProtKB:A8CAH4 | InterPro | 364 | |||
| UniProtKB:F1QZU4 | InterPro | 364 | |||
| UniProtKB:A0A8M3B305 | InterPro | 276 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kiss1rb-201
(1)
|
Ensembl | 1,095 nt | ||
| mRNA |
kiss1rb-202
(1)
|
Ensembl | 720 nt | ||
| mRNA |
kiss1rb-203
(1)
|
Ensembl | 970 nt | ||
| mRNA |
kiss1rb-204
(1)
|
Ensembl | 1,179 nt | ||
| mRNA |
kiss1rb-205
(1)
|
Ensembl | 1,029 nt |
Interactions and Pathways
No data available
Plasmids
No data available