Gene

kiss1rb

ID

ZDB-GENE-060526-54

Name

KISS1 receptor b

Symbol

kiss1rb Nomenclature History

Previous Names

kiss2r (1)
KissR3 (1)
si:ch211-157p22.8

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Enables neuropeptide receptor activity. Acts upstream of or within positive regulation of DNA-templated transcription. Located in cell surface; cytoplasm; and nucleus. Is expressed in several structures, including brain; fat cell; head; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in central precocious puberty 1; hypogonadism; and hypogonadotropic hypogonadism 8 with or without anosmia. Orthologous to human KISS1R (KISS1 receptor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 5 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kiss1rb Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
central precocious puberty 1	Alliance	?Precocious puberty, central, 1	176400
hypogonadotropic hypogonadism 8 with or without anosmia	Alliance	Hypogonadotropic hypogonadism 8 with or without anosmia	614837

Associated With kiss1rb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR017452	GPCR, rhodopsin-like, 7TM
Family	IPR000276	G protein-coupled receptor, rhodopsin-like
Family	IPR000405	Galanin receptor family
Family	IPR008103	KiSS-1 peptide receptor

Domain Details Per Protein

Protein	Length	Galanin receptor family	GPCR, rhodopsin-like, 7TM	G protein-coupled receptor, rhodopsin-like	KiSS-1 peptide receptor
UniProtKB:A0A0R4ILQ2 InterPro	89
UniProtKB:A8CAH4 InterPro	364
UniProtKB:A0A2R8RMI5 InterPro	47
UniProtKB:F1QZU4 InterPro	364
UniProtKB:I6LNU4 InterPro	47
UniProtKB:I6LNU1 InterPro	364
UniProtKB:I6LNU5 InterPro	88
UniProtKB:I6LNU3 InterPro	239
UniProtKB:A0A0R4ID13 InterPro	141
UniProtKB:I6LNU2 InterPro	141
UniProtKB:A0A0R4IGC1 InterPro	239