ZFIN is now using GRCz12tu for Genomic Data
Gene
cfap251
- ID
- ZDB-GENE-060526-328
- Name
- cilia and flagella associated protein 251
- Symbol
- cfap251 Nomenclature History
- Previous Names
-
- si:dkey-65b12.4 (1)
- wdr66
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be active in sperm flagellum. Human ortholog(s) of this gene implicated in spermatogenic failure 33. Orthologous to human CFAP251 (cilia and flagella associated protein 251).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Bielczyk-Maczyńska et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spermatogenic failure 33 | Alliance | Spermatogenic failure 33 | 618152 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR050630 | WD repeat Echinoderm Microtubule-associated Protein-like |
| Homologous_superfamily | IPR011047 | Quinoprotein alcohol dehydrogenase-like superfamily |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | EF-hand domain pair | Quinoprotein alcohol dehydrogenase-like superfamily | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily | WD repeat Echinoderm Microtubule-associated Protein-like |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PR50 | InterPro | 917 | ||||||
| UniProtKB:A0A2R8RY46 | InterPro | 963 | ||||||
| UniProtKB:A0A8M9Q1S6 | InterPro | 537 | ||||||
| UniProtKB:F1Q8Y1 | InterPro | 963 | ||||||
| UniProtKB:A0ACD6B630 | InterPro | 963 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers