Gene

man2a1

ID

ZDB-GENE-060526-31

Name

mannosidase, alpha, class 2A, member 1

Symbol

man2a1 Nomenclature History

Previous Names

si:ch211-131c14.1

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Predicted to have alpha-mannosidase activity. Predicted to be involved in N-glycan processing; mannose metabolic process; and protein deglycosylation. Predicted to localize to Golgi membrane. Orthologous to human MAN2A1 (mannosidase alpha class 2A member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Bergen et al., 2017

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With man2a1 Human Ortholog

No data available

Associated With man2a1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000602	Glycoside hydrolase family 38, N-terminal domain
Domain	IPR011682	Glycosyl hydrolase family 38, C-terminal
Domain	IPR015341	Glycoside hydrolase family 38, central domain
Homologous_superfamily	IPR011013	Galactose mutarotase-like domain superfamily
Homologous_superfamily	IPR011330	Glycoside hydrolase/deacetylase, beta/alpha-barrel
Homologous_superfamily	IPR013780	Glycosyl hydrolase, all-beta
Homologous_superfamily	IPR027291	Glycoside hydrolase 38, N-terminal domain superfamily
Homologous_superfamily	IPR028995	Glycoside hydrolase families 57/38, central domain superfamily
Homologous_superfamily	IPR037094	Glycoside hydrolase family 38, central domain superfamily