Gene
srgap3
- ID
- ZDB-GENE-060524-4
- Name
- SLIT-ROBO Rho GTPase activating protein 3
- Symbol
- srgap3 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of cell migration. Predicted to act upstream of or within signal transduction. Predicted to be active in cytoplasm. Orthologous to human SRGAP3 (SLIT-ROBO Rho GTPase activating protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zheng et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from van Dam et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | AH/BAR domain superfamily | F-BAR domain | FCH domain | Rho GTPase-activating protein domain | Rho GTPase activation protein | SH3 domain | SH3-like domain superfamily | SLIT-ROBO Rho GTPase-activating | srGAP1/2/3, SH3 domain |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IAE2 | InterPro | 1094 | |||||||||
| UniProtKB:E7EYC8 | InterPro | 1070 |
1 - 2 of 2
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
srgap3-201
(1)
|
Ensembl | 5,100 nt | ||
| mRNA |
srgap3-205
(1)
|
Ensembl | 4,197 nt | ||
| ncRNA |
srgap3-002
(1)
|
Ensembl | 881 nt | ||
| ncRNA |
srgap3-003
(1)
|
Ensembl | 468 nt | ||
| ncRNA |
srgap3-004
(1)
|
Ensembl | 539 nt |
1 - 5 of 5
Interactions and Pathways
No data available
Plasmids
No data available